This program is designed to provide the experience of Psilocybin microdosing .
Is the ability for neurons to form and reorganize synaptic connections in the brain. These action potentials (nerve impulses) are transmitted messages across a synapse to neighbouring cells. The creation of more synaptic connections throughout the brain implicates the ability for the brain to ‘unlearn’ old habits while creating new connections with greater creative potential. People suffering from depression, post-traumatic stress disorder, and other mood disorders often exhibit fewer synaptic connections, or have fewer overall neurons functioning within specific parts of the brain.
Psilocybin has been shown to allow for neurons to communicate through connections not previously used, which increases cross-communication with different parts of the brain resulting in more flexible and creative thought
The creation of new pathways throughout the brain — more neuron connections, new neurons, stronger neuron connections, and better neuron response — are all ways in which psilocybin aids in the neuroplasticity of the brain. New pathways for excelling learned behaviors and forming strong memories.potentials.
Divergent thinking is the process of generating creative ideas by exploring numerous and often disparate possible solutions in an emergent cognitive fashion. New neuron connections stimulated by psilocybin through different parts of the brain allow for more novel and creative solutions.
Flow-State (DMN Suppression)
The Default Mode Network (DMN) is a network of interacting brain regions. The DMN is shown to be activated when recalling information, thinking about the future, daydreaming, thinking of the self (ego), and thinking of others. Recent research has shown that an overactive DMN is often present in depressed people.
When performing certain goal-orientated tasks, the DMN has shown to be deactivated. Post psilocybin doses, subjects report heightened ability to get into ‘flow-states’ where the DMN is deactivated, and creative, focus driven tasks are heightened and prolonged.
Cessation Habits (nicotine, alcohol, etc.)
Early studies with psychoactive compounds in the 1960’s were centered around their purposed effects in treating alcohol and nicotine addictions with very high degrees of success (Sherwood et al., 1962). With the resurgence of new energy and institutional support, scientists are again finding very strong evidence that compounds like psilocybin and LSD are very effective at combatting substance abuse.
For those suffering mood and anxiety disorders studies have shown that psilocybin has the ability to increase “emotional and brain plasticity”, increases in functional connectivity throughout the brain, in addition to profoundly reducing, “processing of negative affective stimuli”, which in turn increases overall positive long-lasting mood in humans.
Results from fMRI imaging showed that psilocybin, when acting within the brain as an agonist to 2A serotonin receptors, “acutely reduces amygdala activity and connectivity when viewing negative emotional facial
psilocybin’s acute effect of reducing the amygdala activity has incredible implications in treating mood disorders.expressions.”
Neurogenesis is the growth of neurons (brain cells), and while it was once thought that after birth it was only a matter of destroying brain cells and never making them, it is now thought that a few very specific areas with strict limitations, can actually grow neurons in an adult brain.
Stronger Memory Creation
The potential for new neurons to be formed in the dentate gyrus of the adult brain where sensory data is turned into memories, demonstrates the possibility of forming stronger and more organized memories with increased communication across more synapses between nerve cells.
Using rabbits and mice, studies on both LSD (at higher doses) and psilocybin (at lower doses) have demonstrated an enhanced rate of learning a new conditioned behavior. How is this relevant to PTSD and neurogenesis? Because neurogenesis in the hippocampus could play a part of the acquisition of new behaviors, psychedelic compounds may ‘erase’ pattern recognition through newly formed neurons and neural pathways. Hence the ability for a mouse to ‘erase’ a traumatic event and learn a new conditioned behavior in its place. While very few studies have been done in this area, the implications are very encouraging that in conjunction with cognitive behavioral therapy, psilocybin, or other psychedelic compounds may provide very strong therapeutics for PTSD.
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