How to use Paroxetine? (Paxil, Pexeva, Seroxat) – Doctor Explains

In this video we will cover everything you need to know about Paroxetine, also known as Paxil. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:

Generic name: Paroxetine.
Brand names: Paxil, Pexeva and Seroxat.
Available as a tablet and a suspension.

How to use it?
Tablet: Swallow the tablet completely with half a glass of water.
Suspension: Add the correct amount of powder to half a glass of water and drink it completely. Afterwards rinse your cup with water and drink that water as well.

Duration of treatment:
Furthermore if Paroxetine has no effect within 8-16 weeks, it is probably not effective for you. However if it is effective, you should usually keep using it for 6 months up to several years.

When to use it?
Paroxetine is part of a group of drugs called Specific Serotonin Re-uptake Inhibitor (SSRI). It selectively inhibits the serotonin uptake in your brain. Paroxetine can be used to treat several mental health conditions:
In adults it is used to treat:
– Depression
– Obsessive Compulsive Disorder (OCD)
– Panic disorder with or without agoraphobia
– Social phobia
– Generalized Anxiety Disorder
– Posttraumatic stress disorder

What is the correct dosage?
Unfortunately I can’t provide you with guidelines for the correct dosages, as these differ a lot depending on the specific indication, the side effects you experience and the severity of your complaints. Therefore always use the prescribed dose and frequency your doctor gave you.

However the usual dose most doctors prescribe for an adult will be 10-20mg 1x day. If needed this can be further increased with steps of 10mg to a maximum of 50-60mg a day depending on your indication of use.

What are the side-effects?
Very common (10%): nausea and sexual dysfunction.
Common (1-10%): Increase in cholesterol, drowsiness, decreased concentration, sweating, muscle weakness, insomnia, agitation, abnormal dreams, dizziness, visual disturbances, yawning, constipation, diarrhea, dry mouth, weight gain, headache and decreased appetite
Uncommon (0.1-1%): abnormal bleeding, confusion, hallucinations, fast heart rate, increase or decrease in blood pressure, rash, itching and urinary incontinence.
Rare (0.01-0.1%): mania, anxiety, convulsions, restless leg syndrome, slow heart rate, menstrual disorder and muscle pain.

You should be careful to combine Paroxetine with alcohol. As this might increase the dazing effect of this drug.
In addition it is usually safe to drive while using Paroxetine, however it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects then please do not drive.
Furthermore, Paroxetine can have interactions with several drugs. Therefore always discuss this with your treating physician.

Pregnancy and Lactation:
Paroxetine can be dangerous in both cases, however there are some exceptions. Therefore always discuss this with your doctor.

– Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. –

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1: Farmacotherapeutisch Kompas. (2020). Paroxetine.
2: (2020). Paroxetine.

* The images in this video are used for educational purposes only. Most of the images and video material in this video come from

1. Verified Picasso, Fish Room
2. Patrick Patrikos, Good Times
3: Patrick Patrikios, Rockville
4: Patrick Patrikios, Grut

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Source: Youtube